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“Unmet treatment needs may drive Australian patients with moderate-to-severe AD to higher levels of care. In a study of patients who presented with a dermatologic problem to a tertiary-care emergency department, 27% were determined to have AD at time of discharge—a higher proportion than any other single diagnosis .”

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 “Cross-sectional surveys describe the burden of AD among both Canadian adults and children (and their caregivers) with moderate-to- severe AD, particularly sleep loss and mental health impacts. Access to specialized dermatologic care is a widespread problem for both Canadian children and adults with AD. “

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 “The impacts of AD on missed work, the choice of work, and the timing of retirement were well-represented in the Danish literature, and other countries may find it useful to conduct similar assessments of these impactful and yet often forgotten consequences of AD.“

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 “The French literature is notable for its nuanced analysis of the impacts of AD on the sexual health of both patients and their partners. The French literature also includes several studies which detail the mental health burden experienced by patients.”

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“A major development in Germany has been the successful implementation of educational interventions, with improvements in the quality of life parameters of both children with AD and their caregivers as well as a reduction in disease severity.”

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“Sleep disturbances were common in both children with AD and their caregivers and, as in most other countries in the report, topical steroid risks were a significant concern for parents.”

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 “Providers tend to focus on visible disease manifestations, but many patients care just as much about improving quality of life, reducing itch, improving sleep, and alleviating mental health symptoms.”

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 “An AD diagnosis confers a much greater financial burden on US patients than on patients in other countries. 42.6% of patients with moderate-to-severe disease paid $1000 or more in annual OOP expenses, and 8.5% paid $5000 or more.”

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